Synthesis and Evaluation of Selected Benzimidazole Derivatives as Potential Antimicrobial Agents
نویسندگان
چکیده
منابع مشابه
Synthesis and Evaluation of Selected Benzimidazole Derivatives as Potential Antimicrobial Agents.
A library of 53 benzimidazole derivatives, with substituents at positions 1, 2 and 5, were synthesized and screened against a series of reference strains of bacteria and fungi of medical relevance. The SAR analyses of the most promising results showed that the antimicrobial activity of the compounds depended on the substituents attached to the bicyclic heterocycle. In particular, some compounds...
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Objective: The aim of the present work was to synthesize and characterize a series of 6substituted benzimidazole-2-carbamic acid derivatives and evaluate them for antimicrobial activity. Methods: A novel series of 6-substituted benzimidazole-2-carbamic acid derivatives (6a-f) were synthesized by reacting substituted benzyl chlorides (2a-c) with 4-hydroxy -2nitro aniline (3) in the presence of a...
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ژورنال
عنوان ژورنال: Molecules
سال: 2015
ISSN: 1420-3049
DOI: 10.3390/molecules200815206